Mavericks Wanted
When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement…read on
In 2015, we pioneered a โmoneyball for biotechโ approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allowsโฏscience and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rareย disease, andย develop life-changing medicines for patients with unmet needs as fast as humanly possible.
Together we define white space, push boundaries, and empower people to solve problems. If you’re someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we’llย askย ”why not?” and help reengineer the future of biopharma. At BridgeBio, we value curiosity and experimentationโincluding the ethical & thoughtful use of AI to improve clarity, speed, and quality of work.
What You’ll Do
The Associate Director, Process Chemistry will be responsible for supporting drug substance related activities, both externally and internally. They will interface directly with CROs, CDMOs and others to execute on-time delivery and ensure phase appropriate process procedures are followed. Internally, they will interface with both CMC and members of other departments to effectively execute their drug substance project needs.
Responsibilities
- Oversee contract development and manufacturing organizations (CDMOs) to Process Chemistry activities for drug substance (DS) with a focus on late stage and validation, working across both International and US based CDMOโs. Additionally, provide on-site technical support at CDMOโs on an as-needed basis to oversee various manufacturing/scale-up/validation activities and provide technical expertise to troubleshoot manufacturing/packaging process issues
- Author and manage request for proposal documents to initiate work at CDMOโs
- Support and author DS content for CMC Regulatory for US and Rest of World with focus on late-stage development and marketing applications
- Support Quality Assurance audits, on site at CDMOโs or remotely, as a technical subject matter expert, as needed
- Proactively interface effectively with other CMC team members (e.g., Analytical Chemistry, Formulation Development, Quality Assurance, Supply Chain, etc.)
- Regularly and clearly communicate Process Chemistry both verbally and in visual presentation form, efficiently and contextually
Where You’ll Work
This a U.S-based remote role that will require quarterly, or as needed visits to our San Francisco Office.
Who You Are
- PhD. in Organic Chemistry from Purdue University
- 7+ years as a process chemist in industry
- Experience leading route scouting, process development, scale-up, DOE, process validation, and CMC strategies for small molecule drug substances
- Additional experience with authoring and reviewing regulatory documents, including INDs, NDAs, MAAs, CBE30, and Type II submissions.
At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.
Salary
$177,400โ$205,200 USD
As a global company, our comprehensive benefits may vary based on location.ย We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.
For BridgeBio Full-Time U.S Based Roles:
Financial & Rewards
Market-leading compensation
401(k) with employer match
Employee Stock Purchase Program (ESPP)
Pre-tax commuter benefitsย (transit and parking)
Referral bonusย for hired candidates
Subsidized lunch and parkingย on in-office days
Health & Well-Being
100% employer-paid medical, dental, and vision premiumsย for youย andย your dependents
Healthย Savings Account (HSA)ย with annual employer contributions, plusย Flexible Spending Accounts (FSA)
Fertility & family-forming benefits
Expanded mental health supportย (therapy and coaching resources)
Hybrid work modelย with flexibility
Flexible, โtake-what-you-needโ paid time offย and company-paid holidays
Comprehensive paid medical and parental leaveย to care for yourself and your family
Skill Development & Career Paths:
People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility
We provide career pathing through regular feedback, continuousย educationย and professional development programs via LinkedIn Learning,ย LifeLabs, &ย BetterUpย Coaching
We celebrateย strong performanceย with financial rewards, peer-to-peer recognition, and growth opportunities
By applying, you acknowledge that BridgeBio will process your personal information as described in ourGlobal Candidate Privacy Notice.
